Population genetics: Coalescence theory II

نویسنده

  • Peter Beerli
چکیده

The coalescent is an accumulation of waiting times. We can think of it as standard queuing process where the times are exponentially distributed with rate k(k − 1)/(2 × 2N) [for most elaboration in this chapter I use the Wright-Fisher model as a guide, for the Moran model the rate would be k(k−1)/(2× (2N)2) ]. The coalescent makes no assumptions about the interaction of the intervals, we will assume that the intervals with k = n lineages is independent from the interval with k = n−1 lineages, and we further assume that the exponential distribution is a good approximation to the process (which it is), then we find that the variance of the time to the most recent common ancestor

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تاریخ انتشار 2005